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l-asparaginase

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l-asparaginase
Oncology A chemotherapeutic used for lymphomas and lymphocytic leukemia Adverse effects Vomiting, hepatic dysfunction, allergic reaction, lethargy


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The Company secured the future supply of L-asparaginase, the active ingredient used in the production of Oncaspar, along with an agreement to transfer of the cell line and manufacturing capabilities to its own supplier by December 31, 2009.
Oncaspar is a form of L-asparaginase enhanced with Enzon's PEGylation technology for the treatment of Acute Lymphoblastic Leukemia or ALL.
L-asparaginase is an enzyme that depletes the amino acid asparagine, which certain leukemic cells are dependent upon for survival.
 
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