FABP1

(redirected from L-FABP)
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FABP1

A gene on chromosome 2p11 that encodes a hepatic fatty acid-binding protein that binds long-chain fatty acids, other hydrophobic ligands and bile acids; it may be involved in intracellular lipid transport.
References in periodicals archive ?
In the present study, L-FABP mRNA expression was increased by CORT-induced stress, which may enhance the absorption of non-esterified fatty acid by intestinal epithelium from digesta.
CORT treatment caused an increased expression of SGLT1, CaBP-D28k, PepT1 mRNA in the duodenum and L-FABP mRNA in the jejunum as a compensation for the loss of absorptive area of the small intestine.
The primer sequence of different nutrient transporters and the house-keeping gene [beta]-actin for quantitative RT-PCR Name Oligo Primer sequence SGLT1 Forward primer 5'-GATGTGCGGATACCTGAAGC-3' Reverse primer 5'-AGGGATGCCAACATGACTGA-3' PepT1 Forward primer 5'-TACGCATACTGTCACCATCA-3' Reverse primer 5'-ATGGATGGGAAGGAGCTACAA-3' CaBP-D28k Forward primer 5'-ATGGATGGGAAGGAGCTACAA-3' Reverse primer 5'-TGGCACCTAAAGAACAACAGGAAAT-3' L-FABP Forward primer 5'-GAAGGGTAAGGACATCAA-3' Reverse primer 5'-TCGGTCACGGATTTCAGC-3' [beta]-actin Forward primer 5'-CCACCGCAAATGCTTCTAAAC-3' Reverse primer 5'-AAGACTGCTGCTGACACCTTC-3' Name Predicted size (bp) Genebank accession SGLT1 225 AJ236903 PepT1 205 AY029615 CaBP-D28k 194 M14230 L-FABP 219 NM_204192 [beta]-actin 175 NM_205518 Table 2.
A paired Wilcoxon signed-rank test was used to assess any difference between the increases in serum L-FABP, ALT, and [alpha]-GST.
Healthy individuals had a median plasma L-FABP concentration of 9.