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kynurenic acid
(redirected from Kynurenic)

   Also found in: Dictionary/thesaurus, Wikipedia 0.15 sec.
kynurenic acid /kyn·uren·ic ac·id/ (kin″u-ren´ik) a bicyclic aromatic compound formed from kynurenine in a pathway of tryptophan catabolism and excreted in the urine in several disorders of tryptophan catabolism.
kyn·u·re·nic acid (kny-rnk, -rnk, kn-)
n.
A crystalline acid occurring in the urine as a product of the metabolism of tryptophan.


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The lead author's laboratory studied the effects of a broad-spectrum glutamate receptor antagonist, kynurenic acid (KYNA), on glutamate- and noise-induced trauma in guinea pigs.
In addition, there is increasing evidence that an imbalance in the levels of kynurenic acid, a natural neuromodulator in the brain, is associated with schizophrenia.
 
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