polyarteritis nodosa (redirected from Kussmaul-Maier disease)

polyarteritis no·do·sa (n-ds)

n.

Systemic inflammation and necrosis occurring in medium-sized or small arteries. Also called Kussmaul's disease, periarteritis nodosa.

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polyarteritis nodosa Periarteritis nodosa Internal medicine A connective tissue disease, characterized by necrotizing vasculitis of small to medium-sized arteries, affecting multiple organ systems–GI tract, kidneys, liver, muscle, skin; in > 50%, vasculitis affects peripheral nerves as mononeuritis multiplex or symmetric sensorimotor polyneuropathy Clinical Fever, malaise, myalgia Lab ↑ WBCs, ↑ ESR, 30-50% have HBsAg or HBsAb Management Immunosuppression–eg, prednisone, cyclophosphamide yields ± 90% 5-yr survival