Kupffer cells


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Kupf·fer cells

(kūp'fĕr),
phagocytic cells of the mononuclear phagocyte series found on the luminal surface of the hepatic sinusoids.

Kupffer cells

[koo͡p′fərz]
Etymology: Karl W. von Kupffer, German anatomist, 1829-1902
immobile macrophages that line liver sinusoids. Kupffer cells filter bacteria and other foreign proteins from the blood and initiate immune responses.

Kupf·fer cells

(kup'fĕr selz)
Phagocytic cells of the mononuclear phagocyte series found on the luminal surface of the hepatic sinusoids.

Kupffer cells

Fixed MACROPHAGE cells that line the fine blood sinuses (capillaries) of the liver and act as scavengers to remove senescent red blood cells, bacteria and other foreign material. (Karl Wilhelm von Kupffer, 1829–1902, German anatomist)

Kupffer,

Karl W. von, German anatomist, 1829-1902.
Kupffer cell sarcoma
Kupffer cells - phagocytic cells of the mononuclear phagocyte series found on the luminal surface of the hepatic sinusoids. Synonym(s): stellate cells of liver
References in periodicals archive ?
Between the cords of hepatocytes the sinusoids were lined with endothe-lial cells having flattened dark nuclei and Kupffer cells with nuclei projecting into the sinusoids which opened into the central vein.
Morphometric Observations: The details of Volume density of hepatocytes (Vvh) and Numerical density of Kupffer cells on the area (Nak) are summarized in Table 4.
The role of Kupffer cells and reactive oxygen species in hepatic injury during acute and chronic alcohol intoxication.
It is proposed that Kupffer cells are stationary and regenerate after liver trauma by local proliferation (Bair et al.
4] for a similar period showed dose- and duration-dependant protective effects, such as diminution of fibrosis and fatty changes, while dilated blood sinusoids, vacuolar degeneration and hypertrophy of Kupffer cells were also seen, when compared to the liver sections of rats intoxicated with [CCl.
Research funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA)/National Institutes of Health (NIH) first identified the importance of Kupffer cells and their response to endotoxin in the progression of liver disease (Thurman et al.
These functional alterations were accompanied by some histological alterations, like congestion of the central vein, some polymorphonuclear inflammatory cells infiltrate, sinusoids walls showing numerous Kupffer cells with swelling lumen by the blood cells (Figure 5).
Our findings were further supported by the histopathological examination of liver section, which illustrated that liver tissue of NDEA-treated rats showed drastic changes in the morphology of the liver cells, manifest as nuclear pleomorphism, intranuclear vacuoles, cellular infiltration, pyknotic nuclei and numerous Kupffer cells.
Malaria circumsporozoite protein inhibits the respiratory burst in Kupffer cells.
Kupffer cells, endothelial cells, periportal nondescript cells).
Kupffer cells (liver macrophages) in the blood pass through the hepatic sinusoids and in fibrosis become activated by adverse stimuli such as viruses or toxins.
37) Normal splenic tissue, as well as Kupffer cells of the liver, predominantly filters these superparamagnetic iron oxides, rendering the contrast agent tissue specific.