Kupffer cell


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Kupffer cell

(ko͝op′fər)
n.
A macrophage found in the liver. Kupffer cells line the walls of the sinusoids.

Kupffer cell

(koop'fer)
[Karl W. von Kupffer, Ger. anatomist, 1829–1902]
A macrophage of the liver. See: liver
References in periodicals archive ?
LPS-induced activation of this receptor complex on Kupffer cells triggers downstream signaling kinases (i.
5[degrees]C) on Numerical density of Kupffer cells on the area (Nak) Experimental Morphometric Controls 02 Days Parameter (n = 6) (n = 6) Nak 4905.
In addition to producing cytokines, activated Kupffer cells are the major source of ROS in the liver, which, in large amounts, can lead to oxidative stress.
C, Schistosome pigment is often seen within Kupffer cells (courtesy of Joseph Misdraji, MD) (hematoxylin-eosin, original magnifications X150 [A and B] and X300 [C]).
D) Oval cell hyperplasia (arrowheads) and increased Kupffer cells within sinusoids (Kupffer cell hyperplasia) in a male mouse exposed to 50 ng BPA/kg maternal diet.
4]administration oxidant induced activation of kupffer cells occur, with the release of proinflammatory cytokines like tumor TNF-[alpha], TGF-[beta] and IL-6.
CONCLUSION: Postoperative hyperbilirubinemia is seen in most of cases of acute abdomen and these is found to be clue to circulating endotoxins which may impair the excretion of bilirubin by biliary canaliculi and also bacterial load overwhelms kupffer cells function and may cause hepatocyte dysfunction.
As evident in Figures 2 and 3, there were degenerative changes such as ballooning degeneration, Kupffer cell hyperplasia, single cell necrosis/drop out as well as foci of necrosis, sinusoidal compression, and disruption of liver cell plates in the liver of 5 days exposed animals.
Mild siderosis can be seen in severe Kupffer cell siderosis, alcoholic liver disease, nonalcoholic fatty liver disease, and hepatitis B and C.
A new view of the roles of blood flow dynamics and Kupffer cell in intrahepatic metastasis of hepatocellular carcinoma.
Conspicuity of hepatocellular nodular lesions in cirrhotic livers at ferumoxides-enhanced MR imaging: Importance of Kupffer cell number.
M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver disease," Hepatology, vol.