Nomadic or sessile: can Kupffer
cells function as portals for malaria sporozoites to the liver?
cells, endothelial cells, periportal nondescript cells).
cells (liver macrophages) in the blood pass through the hepatic sinusoids and in fibrosis become activated by adverse stimuli such as viruses or toxins.
La vesicula de Kupffer
se observo en la posicion extrema caudal.
Accumulation of hepatic (liver) hemoside rin in Kupffer
cells (macrophages) was noted as an indicator of cachexia.
Las EROs pueden danar en forma directa, alterando biomoleculas esenciales, con la consiguiente perdida de su funcion biologica y viabilidad celular; (7) o bien indirectamente, por activacion en las celulas de Kupffer
y otras celulas no parenquimatosas, de factores de transcripcion redox-sensibles, como el NF-[kappa]B y el AP-1, los que a su vez gatillan la sintesis de mediadores proinflamatorios, citotoxicos y fibrogenicos.
Problems such as Kupffer
cell dysfunction, microcirculatory changes, ATP depletion, the generation of reactive oxygen species, and increased leukocyte adhesion resulting from the ischemia reperfusion period of the liver transplantation sometimes lead to graft failure or primary nonfunction of the liver.
Sato's team found that, while Kupffer
cells in the liver decompose endotoxin, the same cells also produce a substance called cytokines (TNF-alpha), which destroys surrounding cells in the liver and cause inflammation.
Eighty-five to ninety percent of all blood that leaves the stomach and intestines carries ingested substances directly to the liver, where macrophages (Greek for "big eaters") or Kupffer
cells remove large amounts of debris and bacteria.
In the liver, multiple types of cells are damaged--including hepatocytes, Kupffer
cells, and hepatic stellate cells (Clin.
case-patient who underwent biopsy; however, IHC revealed rare YF virus antigen within Kupffer