Krabbe's disease


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Related to Krabbe's disease: Gaucher's disease

Krabbe's disease

 [krah´bez]
a familial form of leukoencephalopathy beginning in infancy, in which the sphingolipid ceramide galactoside accumulates in the tissues due to a deficiency of β-galactosidase, marked pathologically by cerebral demyelination and by the presence of large globoid bodies in the white substance.

Krabbe's disease

Krabbe's disease

See GLOBOID CELL LEUKODYSTROPHY.

Krabbe's disease

see globoid cell leukodystrophy.
References in periodicals archive ?
Serial DTI scans, including pre- and posttransplantation imaging, have also been performed to prospectively compare the anisotropy measurements of white matter regions in Krabbe's disease patients treated with early (0 to 1 month) and late (1 to 12 months) stem cell transplantation.
identified 11 babies before or soon after birth who had the enzyme deficiency but hadn't yet shown signs of Krabbe's disease.
Among these is Krabbe's disease, a rare hereditary condition characterized by a deficiency of galactosylceramidase.
Hunter has Krabbe's disease, a rare, incurable, hereditary disorder which takes the life of most babies within the first 13 months.
She had Krabbe's disease, an incurable degenerative disorder of the nervous system which would slowly take away her sight, senses, mobility and ultimately her life.