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knockout mouse
(redirected from Knockout mice)

   Also found in: Wikipedia 0.01 sec.
knockĀ·out mouse (nkout)
n.
A transgenic mouse that has been genetically engineered to exhibit mutations in specific genes.

knockout mouse,
a mouse that has had a specific gene artificially deleted from its genome.


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Transgenic is now generating a library of two thousand novel knockout mice that could be used in drug targeting.
Experiments in cultured cells and in knockout mice have hinted that DJ-1 mutations may sensitize cells to the harmful effects of oxidative stress.
demonstrated a decreased bacteremia with antibody blockade of chemokine receptors (CXCR2) and in CXCR2 knockout mice (33).
 
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