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knockout mouse
(redirected from Knockout mice)

    Also found in: Wikipedia 0.06 sec.
knock·out mouse (nkout)
n.
A transgenic mouse that has been genetically engineered to exhibit mutations in specific genes.
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Transgenic is now generating a library of two thousand novel knockout mice that could be used in drug targeting.
Not so generic mice: Japanese companies venture into the transgenic ... by La Madeleine, Bonnie Lee / Japan Inc.
Experiments in cultured cells and in knockout mice have hinted that DJ-1 mutations may sensitize cells to the harmful effects of oxidative stress.
PD gene and oxidative stress by Phillips, Melissa Lee / Environmental Health Perspectives
demonstrated a decreased bacteremia with antibody blockade of chemokine receptors (CXCR2) and in CXCR2 knockout mice (33).
Human granulocytic anaplasmosis and Anaplasma phagocytophilum by Bakken, Johan S. / Emerging Infectious Diseases
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