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Klinefelter's syndrome |
Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson | 0.24 sec. |
Klinefelter's syndrome Chromosomal abnormality characterized by small testes and male infertility. Mentioned in: Follicle-Stimulating Hormone Test Klinefelter's syndrome a condition in humans characterized by the presence of small testes, with fibrosis and hyalinization of the seminiferous tubules, impairment of function and clumping of Leydig cells, and an increase in urinary gonadotropins, associated with an abnormality of the sex chromosomes. It is associated typically with an XXY chromosome complement. A similar condition is seen in male tortoiseshell and white cats, and has been recorded rarely in stallions, bulls, rams and dogs. |
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| The study sample of 37 participants includes ten persons with complete androgen insensitivity (CAIS), five with partial androgen insensitivity (PALS), four women with CAH, two women with progestogen-induced clitoromegaly, one each of Klinefelter's syndrome in a male and Turner's syndrome in a female, six miscellaneous patients including gonadal dysgenesis, micropenis, true hermaphroditism, and at least two with hypospadias, plus eight for whom the diagnosis is unknown. I was diagnosed 12 years ago with Klinefelter's syndrome, which has as a symptom low testosterone ("Unproven Elixir," SN: 5/10/03, p. Chromosomal problems such as Down's syndrome, Turner's syndrome, or Klinefelter's syndrome are not inherited in the sense that a parent must either have the condition or be a carrier of the corresponding genes; rather, such conditions result from errors in the transmission of genetic material. |
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Klinefelter's syndrome
