Klinefelter's syndrome (redirected from Klinefelter)

Kline·fel·ter's syndrome (klnfltrz)

n.

A chromosomal anomaly in males characterized by the presence of two X-chromosomes and one Y-chromosome, causing reduced testicular size, seminiferous tubule dysgenesis, and infertility. Also called XXY syndrome.

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Klinefelter's syndrome

Chromosomal abnormality characterized by small testes and male infertility.

Mentioned in: Follicle-Stimulating Hormone Test

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Klinefelter's syndrome

a condition in humans characterized by the presence of small testes, with fibrosis and hyalinization of the seminiferous tubules, impairment of function and clumping of Leydig cells, and an increase in urinary gonadotropins, associated with an abnormality of the sex chromosomes. It is associated typically with an XXY chromosome complement. A similar condition is seen in male tortoiseshell and white cats, and has been recorded rarely in stallions, bulls, rams and dogs.