KISS1R

(redirected from Kisspeptins receptor)

KISS1R

A gene on chromosome 19p13.3 that encodes a Gq/G11 protein-coupled receptor that signals by stimulating phospholipase C, resulting in Ca2+ mobilisation. KISS1R is highly expressed in the pancreas, placenta and brain, and slightly expressed in the small intestine, kidney, lung, liver and heart. It plays a key role in the neuroendocrine control of the gonadotrophin axis and may inhibit metastases.
References in periodicals archive ?
Global Markets Direct's, 'KiSS-1 Receptor (G-Protein Coupled Receptor 54 or G-Protein Coupled Receptor OT7T175 or hOT7T175 or Hypogonadotropin-1 or Kisspeptins Receptor or Metastin Receptor or KISS1R or GPR54) - Pipeline Review, H1 2016', provides in depth analysis on KiSS-1 Receptor (G-Protein Coupled Receptor 54 or G-Protein Coupled Receptor OT7T175 or hOT7T175 or Hypogonadotropin-1 or Kisspeptins Receptor or Metastin Receptor or KISS1R or GPR54) targeted pipeline therapeutics.
The report provides comprehensive information on the KiSS-1 Receptor (G-Protein Coupled Receptor 54 or G-Protein Coupled Receptor OT7T175 or hOT7T175 or Hypogonadotropin-1 or Kisspeptins Receptor or Metastin Receptor or KISS1R or GPR54), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
The report provides a snapshot of the global therapeutic landscape for KiSS-1 Receptor (G-Protein Coupled Receptor 54 or G-Protein Coupled Receptor OT7T175 or hOT7T175 or Hypogonadotropin-1 or Kisspeptins Receptor or Metastin Receptor or KISS1R or GPR54)