angiolymphoid hyperplasia with eosinophilia

(redirected from Kimura disease)

an·gi·o·lym·phoid hy·per·pla·si·a with e·o·sin·o·phil·i·a

solitary or multiple small benign cutaneous erythematous nodules, occurring mainly on the head and neck in young adults, characterized by dermal proliferation of blood vessels with vacuolated histiocytoid endothelial cells and with a varied infiltrate of eosinophils, lymphocytes which may form follicles, and histiocytes.
Synonym(s): Kimura disease

angiolymphoid hyperplasia with eosinophilia

An uncommon idiopathic condition with some features of Kimura disease, which presents in adults as one or more red-blue papules, plaques, or nodules in the head and neck, less commonly in the hands, shoulders, and elsewhere. It is unknown whether it is neoplastic or reactive.
Prognosis ALHE is clinically benign but persistent and treatment is refractory.

Kimura,

Tetsuji, 20th century Japanese pathologist.
Kimura disease - solitary or multiple small benign cutaneous erythematous nodules. Synonym(s): angiolymphoid hyperplasia with eosinophilia
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References in periodicals archive ?
Key words: Angiolymphoid Hyperplasia with Eosinophilia, Kimura Disease, histiocytoid endothelial cell, painless nodule.
Although AHE might mimic superficial form of Kimura disease and the coexistence of the two entities has been reported,11 they are presently considered to be separate entities: AHE lesions are localized in the superficial tissues, while Kimura disease involves deeper tissues such as lymph nodes and salivary glands.
The differential diagnosis includes Masson vegetant or papillary endothelial hyperplasia (a reactive endothelial proliferation associated with organizing thrombus/clot); Kimura disease (lymph node disorder, most often in Asian men, who have peripheral serum eosinophilia, reactive lymphoid follicles, follicular lysis, eosinophilic microabscesses, polykaryocytes, and IgE deposition); and angiosarcoma (freely anastomosing vessels, atypical endothelial cells, increased mitoses, necrosis).
Kimura disease is a rare idiopathic inflammatory disease that presents as painless nodules and masses in the head and neck region.
All the above mentioned features favour the diagnosis of kimura disease.
In the past, ALHE/EH and Kimura disease were thought to be the same entity.
Kimura disease is an uncommon chronic, benign, inflammatory condition of unknown etiology.
Kimura disease is a benign rare chronic inflammatory disorder of unknown etiology that involves the lymph nodes and subcutaneous tissue of the head and neck regions.
INTRODUCTION: Kimura Disease (KD) is a rare chronic inflammatory disorder, which was first described in 1937 by Kim and Szeto in the Chinese literature as "eosinophilic hyperplastic lymphogranuloma" and has been known most often as Kimura's disease since its description by Kimura et al.
Clinically, IPEH can be misdiagnosed as a mucocele, hemangioma, pyogenic granuloma, Kaposi sarcoma, angiosarcoma, Kimura disease, intravenous atypical vascular proliferation, endovascular papillary angioendothelioma, papular angioplasia, or bacillary angiomatosis.
Among the reactive conditions, Kimura disease was considered because of the clinical presentation of a tumorlike swelling in the submandibular subcutaneous area with typical lymphadenopathy.
Kimura disease is a rare, chronic inflammatory disorder that involves subcutaneous tissues, predominantly those in the head and neck region.