killer cells


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kill·er cells

cytotoxic cells involved in antibody-dependent cell-mediated immune responses; they possess receptors for the Fc portion of IgG molecules that lyse or damage IgG-coated target cells without mediation of complement. They are not MHC restricted. See: antibody-dependent cell-mediated cytotoxicity, CD8.
See also: natural killer cells.
Synonym(s): K cell (2) , null cells (1)

kill·er cells

(kil'ĕr selz)
Cytotoxic cells involved in antibody-dependent, cell-mediated immune responses.
Synonym(s): K cells, null cells (1) , T-cytotoxic cells.

killer cells

A subclass of large, granular LYMPHOCYTES that includes the natural killer (NK) cells and the killer (K) cells. These are important elements in the immune system and are the final effectors in the process by which damaged, infected or malignant cells are recognised and destroyed. At this stage in the process, killer cells act in conjunction with activated MACROPHAGES and cytotoxic T cells.
References in periodicals archive ?
Cytokine-induced killer cells eradicate bone and soft-tissue sarcomas," Cancer Research, vol.
Increased susceptibility to liver injury in hepatitis B virus transgenic mice involves NKG2D-ligand interaction and natural killer cells.
Wang D, Ma Y, Wang J, Liu X, Fang M (2013) Natural killer cells in innate defense against infective pathogens.
Her research has also suggested the natural killer cells play a part in preventing implantation of a fertilised egg, including IVF treatment.
Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells.
a substance P antagonist (an experimental agent); they then measured natural killer cell activity in vitro.
Association of depression, CD8+ T lymphocytes, and natural killer cell activity: Implications for morbidity and mortality in human immunodeficiency virus disease.
The study, which found that long-term immune function decreases in proportion to how many times a woman has intentionally lost weight, measured natural killer cell activity in the women's blood.
In the second study, Andrea Velardi, MD and colleagues from Perugia University School of Medicine in Italy reported that natural killer cells in the immune systems of mismatched donors can provide beneficial effects.
The lymph system is composed of a network of vessels that mobilize fluids from every part of our body and groups of lymph nodes that house killer cells of the immune system.
This drug's biologic activities include activation of macrophages and natural killer cells, stimulation of interferon, and reactivation of cytokines.