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ketotifen

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
ketotifen /ke·to·ti·fen/ (-ti´fen) a noncompetitive H and mast cell stabilizer; used topically as the fumarate salt as an antipruritic in the treatment of allergic conjunctivitis.
ketotifen
[ke′toti′fen]
a noncompetitive H1-receptor antagonist and mast cell stabilizer used as the fumarate salt, administered orally in the chronic treatment of children with mild atopic asthma and topically to the conjunctiva as an antipruritic in the treatment of allergic conjunctivitis.

antihistamine 
Any substance that reduces the effect of histamine or blocks histamine receptors, usually the histamine 1 (H1) receptor. It is used in the treatment of allergic conjunctivitis and also in the temporary relief of minor allergic symptoms of the eye. Common agents include antazoline sulfate, azelastine hydrochloride, cetirizine, chlorphenamine, emedastine, epinastine hydrochloride, ketotifen, levocabastine, loratadine and olopatadine. See hypersensitivity; mast cell stabilizers.


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Containing ketotifen fumarate as a main ingredient, the product helps alleviate nasal allergy symptoms due to pollen and house-dust mites.
1) Newer drugs, such as fexofenadine (Allegra), loratadine (Claritin) and cetirizine (Zyrtec), all taken in pill form, as well as the intranasal antihistamine azelastine (Astelin), and ketotifen, an antihistamine drop for your eyes, are less sedating and thus the treatment of choice.
The studies focused on the antimuscarinic (potential for drying side effects) activity of various marketed antihistamines including azelastine, cetirizine, desloratadine, fexofenadine, ketotifen and olopatadine, compared to bilastine and epinastine, related compounds in Inspire's portfolio.
 
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