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ketotifen

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ketotifen /ke·to·ti·fen/ (-ti´fen) a noncompetitive H and mast cell stabilizer; used topically as the fumarate salt as an antipruritic in the treatment of allergic conjunctivitis.
ketotifen
[ke′toti′fen]
a noncompetitive H1-receptor antagonist and mast cell stabilizer used as the fumarate salt, administered orally in the chronic treatment of children with mild atopic asthma and topically to the conjunctiva as an antipruritic in the treatment of allergic conjunctivitis.

ketotifen [ke″to-ti´fen]
a noncompetitive H1-receptor antagonist and mast cell stabilizer; used as the fumarate salt, administered orally in the chronic treatment of children with mild atopic asthma and topically to the conjunctiva as an antipruritic in the treatment of allergic conjunctivitis.

antihistamine 
Any substance that reduces the effect of histamine or blocks histamine receptors, usually the histamine 1 (H1) receptor. It is used in the treatment of allergic conjunctivitis and also in the temporary relief of minor allergic symptoms of the eye. Common agents include antazoline sulfate, azelastine hydrochloride, cetirizine, chlorphenamine, emedastine, epinastine hydrochloride, ketotifen, levocabastine, loratadine and olopatadine. See hypersensitivity; mast cell stabilizers.


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For further analysis, Shi and colleagues took a group of obese and diabetic mice and, for a period of two months, treated them with over-the-counter allergy drugs ketotifen fumarate (also called Zaditor) or cromolyn.
In a study published in the journal Nature Medicine, his team tried out two common over-the-counter allergy drugs, ketotifen fumarate and cromolyn, on lab mice that were obese and diabetic.
He has shown that a 1-mg oral dose of ketotifen results in a 72% brain [H.
 
 
 
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