KLF2

KLF2

A gene on chromosome 19p13.11 that encodes a member of the Kruppel-like family of broadly expressed zinc finger transcription factors, which regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1) and the selectin CD62L.
References in periodicals archive ?
The presence of faults in the KLF2 and NOTCH2 genes indicated that patients generally required intensive treatment for their disease more quickly.
Taking a new approach, the scientists used reprogramming methods to express two different genes, NANOG and KLF2, which reset the cells.
Preliminary data demonstrates elevated expression of Fos, FosB, CEBPB, KLF2 and ZFP36 in the nucleus accumbens of mice abstinent following chronic cocaine exposure, suggesting that these genes could underlie the rewiring of transcriptional complexes observed in abstinent mice.