KLF11

KLF11

A gene on chromosome 2p25 that encodes a zinc finger transcription factor that binds SP1-like sequences in epsilon- and gamma-globin gene promoters, inhibiting cell growth and causing apoptosis.

Molecular pathology
KLF11 mutations are linked to maturity-onset diabetes of the young (type 7).
References in periodicals archive ?
Epigenetic Regulation of Uterine Biology by Transcription Factor KLF11 via Post-translational Histone Deacetylation of Cytochrome p450 Metabolic Enzymes.