CDKN1C

(redirected from KIP2)

CDKN1C

A gene on chromosome 11p15.5 that encodes a strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation.

Molecular pathology
CDKN1C mutation is implicated in sporadic cancers and Beckwith-Wiedemann syndrome, suggesting a role in tumour suppression.
References in periodicals archive ?
Table 3: Comparison of HandE stains with p57 KIP2 IHC results in HM.
The usefulness of p57 KIP2 immunohistochemical staining and genotyp-ing test in the diagnosis of the hydatidiform mole.
Feinberg, IGF2, H19, p57 KIP2, and LIT1 and the Beckwith-Wiedemann Syndrome, in INBORN ERRORS OF DEVELOPMENT: THE MOLECULAR BASIS OF CLINICAL DISORDERS OF MORPHOGENESIS 758, 758-65 (Charles J.