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K-ras gene |
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K-ras gene, a type of oncogene, the activating mutations of which play a key role in neoplastic progression, especially in colorectal, pancreatic, and lung cancer. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Moreover, K-ras gene mutation enhances motility of lung adenocarcinoma cells via Akt activation (18), and radioresistance of K-ras-mutated human tumor is mediated through the epidermal growth factor receptor-dependent PI3K-Akt pathway (19). Arsenite enhances K-Ras gene expression during malignant transformation. Van Laethem et al12 studied the use of K-ras gene analysis on bile duct brushings and found that the sensitivity and specificity of this technique were comparable to those of conventional cytologic evaluation. |
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