Jewish genetic disease

Jewish genetic disease

Any genetic disease that is more common in Jewish populations, especially the Ashkenazi subgroup, due to high rates of endogamy. Most are autosomal recessive and present in childhood. The American College of Medical Genetics recommends routine pre-conceptual or prenatal carrier screening for 9 diseases (Bloom syndrome, Canavan disease, cystic fibrosis, familial dysautonomia, Fanconi anaemia group C, Gaucher disease, mucolipidosis IV, Niemann-Pick disease type A and Tay-Sachs disease), which are common in Jews of eastern European (Ashkenazi) descent. 

Jewish (Ashkenazim) Genetic Diseases
Disease—Incidence—Carrier rate
Gaucher disease—1/900—1/15
Cystic fibrosis—1/2,800—1/29
Tay-Sachs disease—1/3,000—1/30
Familial dysautonomia—1/3,600—1/32
Canavan disease—1/10,000—1/50
Fanconi anemia group C—1/32,000—1/89
Niemann-Pick, type A—1/32,000—1/90
Bloom syndrome—1/40,000—1/100
Mucolipidosis IV—1/63,000—1/127
References in periodicals archive ?
NEW YORK -- In response to alarming new data that only six percent of the American Jewish population is aware of Gaucher (Pronounced "Go-shay") disease -- the most common Jewish genetic disease - the National Gaucher Foundation (NGF) today kicked-off the National Gaucher Awareness Month with the "September Summit" at the Manhattan Jewish Community Center.
The Victor Center was founded by Lois Victor, who herself lost two children to a Jewish genetic disease and was determined to help spare other families the same heartbreak.
Tay-Sachs, the most commonly recognized Jewish genetic disease, was the first for which carrier screening became available in the early 1970s.
A simple blood test is all that is necessary to screen for the current Jewish genetic disease panel of 19.
The AJGS screening held in November 2011 identified twelve of the sixty-two persons screened as carriers of a Jewish genetic disease.
The last AJGS screening in November identified twelve people as carriers of a Jewish genetic disease.
A simple blood test is all that is necessary for screening for the entire Victor Center Jewish genetic disease panel of 19, and individuals, including interfaith couples, should be screened prior to each pregnancy, since with advances in testing, that list is constantly being expanded.
A simple blood test is all that is necessary to screen for the current Jewish genetic disease panel of 19 and all at risk individuals including interfaith couples should be screened with the Jewish partner being screened first.
Promoting the need for screening to potential carriers prior to every pregnancy to help ensure healthy babies is the mission of The Victor Center for the Prevention of Jewish Genetic Diseases, an organization founded by Lois Victor, who herself lost two children to a Jewish genetic disease, and is dedicated to helping to prevent Jewish genetic diseases through high-quality and accessible education, genetic counseling, and screening.
I started the Victor Center because I was looking for a way to spare others what we went through with our two daughters, one of whom died at the age of 8 and the other at 35, both from Familial Dysautonomia - a Jewish genetic disease that is preventable but that has no cure," Ms.
org) is a non-profit, community-based public health initiative dedicated to preventing Jewish genetic diseases.
MOMENT'S UPDATED LISTING OF JEWISH GENETIC DISEASES IS AVAILABLE AT MOMENTMAG.

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