MYOC

(redirected from JOAG)
Also found in: Acronyms.

MYOC

A gene on chromosome 1q23-q24 that encodes myocilin, a protein thought to play a role in cytoskeletal function, which is highly expressed in ocular tissues including the trabecular meshwork, which regulates intraocular pressure.

Molecular pathology
MYOC mutations cause hereditary juvenile-onset open-angle glaucoma.
References in periodicals archive ?
Among the families with Mendelian inheritance, different modes of inheritance have been documented, but in most cases with COAG and JOAG the segregation is autosomal dominant, while PCG follows a recessive pattern of inheritance (Sarfarazi 1997).
A total of 9 families with glaucoma complied with these requirements; seven of them present COAG, one has JOAG and one has PCG.
Various investigations revealed that an Italian company had been commissioned by Cidiverte - JOAG Italy Spa to proceed with the duplication of the game.