KDM4C

(redirected from JMJD2C)

KDM4C

A gene on chromosome 9p24.1 that encodes lysine-specific demethylase 4C, which demethylates histone H3 and generates formaldehyde and succinate.

Molecular pathology
Chromosome defects and increased transcriptional expression of KDM4C are associated with squamous cell carcinoma of the oesophagus.
References in periodicals archive ?
The protein JMJD2C is the key that opens up a whole suite of genes needed for tumors to grow and metastasize, so it represents a potential target for cancer drug development," he said.
Delving deeper, the researchers found that HIF-1 switches on the JMJD2C gene, stimulating production of the protein.
com)-- Novus Biologicals announced today the release of three new rabbit polyclonal antibodies to important histone demethylase proteins: JMJD2C (Catalog# NBP1-49600), JMJD1A (Catalog# NBP1-49601), and JMJD2A (Catalog# NBP1-49602).
JMJD2C and JMJD2A are members of the JHDM3 histone demethylase family.