JARID2

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JARID2

A gene on chromosome 6p24-p23 that encodes an ortholog of the mouse jumonji gene, which encodes a nuclear protein essential for mouse embryogenesis. JARID2 is a regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion and haematopoiesis, modulating histone methyltransferase activity and recruiting histone methyltransferase complexes to their target genes; it downregulates cell proliferation signalling pathways. During embryogenesis, it is primarily expressed in neurons, especially in dorsal root ganglion cells. It interacts with GATA4, NKX2-5, RB1, SUZ12 and ZNF496.
References in periodicals archive ?
In the United States, JMJ developed the Frisco Bridges in Frisco, Texas, and the West World Development in Palm Springs, Calif.
The agreement was signed by QBWA vice-chairwoman Aisha Alfardan and JMJ Associates Middle East director Simon Giffin.
JMJ Group managing director Sachin Joshi said: "We are truly excited about setting up a world class hotel with a world class partner.
Solo para instalar un sistema de emergencias de salud para la JMJ, la alcaldia de Rio de Janeiro gastara 4 millones de dolares.
La JMJ tiene su origen en el "Jubileo Internacional de la Juventud" celebrado el 15 de Abril de 1984 (Domingo de Ramos) en Roma.
El domingo 28, el Papa celebrara la misa y tendra un encuentro con el CELAM y los voluntarios de la JMJ antes de regresar a Roma.
5 April 2012 -- US equity mortgage lender JMJ Financial has struck a deal to purchase a maximum USD1.
She worked with the JMJ sisters in Guntur, in their hospital.
11 CIV 6458) alleging that it held various convertible notes and warrants issued by ACTC and that "by reason of certain transactions between the company and JMJ Financial, Inc.
En ella hace un recorrido muy completo sobre el magisterio pontificio de los siglos XIX y XX dedicado los jovenes, asi como una referencia a diversos mensajes de las JMJ.
Bountiful - JMJ AUTO SALES, a new and used car dealership, opened at 1545 S.
International Resource News-July 7, 2011--AmeriLithium Corp signs financial contract with JMJ Financial(C)1994-2011 ENPublishing - http://www.