ivermectin


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i·ver·mec·tin

(ī'vĕr-mek'tin),
A semisynthetic macrolide antibiotic of the avermectin family of compounds, effective in the treatment of filariasis and many other parasites. The drug destroys Onchocerca microfilaria and Filaria bancrofti. Derived from the soil bacterium, Streptomyces avermitilis. Approved by the FDA for the treatment of scabies by topical administration. Widely used in veterinary medicine in a number of species for control of ectoparasites and endoparasites. Unusual sensitivity (increased toxicity, and sometimes death) in collie-type breeds is well documented.

ivermectin

(ī′vər-mĕk′tĕn)
n.
An anthelmintic and acaricide used to treat parasitic infections in livestock, to prevent heartworm infection in dogs, and to treat onchocerciasis, intestinal strongyloidiasis, and head lice in humans.

ivermectin

A drug used to kill MICROFILARIA in the treatment of ONCHOCERCIASIS and other microfilarial diseases. Ivermectin has also been used to treat severe SCABIES in elderly institutionalized people, but an unusually high death-rate in this group cast doubt on the safety of the application. The drug is on the WHO official list.

ivermectin

parasiticide; single-dose treatment for scabies

onchocerciasis 

A disease caused by infestation with the filarial worm (Onchocerca volvulus) spread by blackflies. It is common in tropical Africa and Central America, especially in areas near rivers. Large numbers of microfilariae are present on the skin and often enter the eye. The patient initially complains of itching, but blindness occurs as a result of chorioretinitis and optic neuritis. The disease is treated successfully with ivermectin. Syn. onchocercosis; river blindness.

ivermectin

an avermectin with broad activity against many helminths and arthropods. A broad-spectrum anthelmintic, acaricide and insecticide, used orally, subcutaneously and as a pour-on.
References in periodicals archive ?
Because of the lack of complete resolution with ivermectin therapy, topical selamectin (23 mg/kg topically q4wk for 2 treatments; Revolution, Pfizer, New York, NY, USA) was initiated.
The difference between ivermectin and vehicle became statistically significant as early as week 4.
Impact of 10 years of diethylcarbamazine and ivermectin mass administration on infection and transmission of lymphatic filariasis.
22,1] reported that the effect of ivermectin seems to depend not only on its parasiticidal action but relies also on an activation of host immunocompetence .
The average number of enumerated larvae in fecal samples of different days after treatment with pour on Ivermectin in table 1 has been shown.
Ivermectin is an antiparasitic medication traditionally used against worms.
The researchers found that 95 percent of the 398 individuals who received Ivermectin were free from lice 15 days after the start of treatment, as compared to 85 percent of the 414 individuals treated with malathion.
Thiabendazole, also known as Mintezol, is less effective than Ivermectin.
These interventions include: cataract surgery to cure the eye disease related to ageing; prevention of trachoma; provision of the drug ivermectin for the treatment of the infectious disease river blindness; immunization against measles; provision of vitamin A supplements for the prevention of childhood blindness; and provision of eyeglasses.
Animals were held for a 2-week quarantine period during which time they were treated for parasitic infections with topical powder and dosages (based on weight) of ivermectin.
A global programme for the elimination of LF has been launched employing mass drug administration (MDA) of annual single dose of a combination of diethylcarbamazine citrate (DEC)/ ivermectin and albendazole (2,3).
have announced that an additional indication of Stromectol Tablets 3mg - generic name ivermectin - has been approved for the administration for scabies treatment under the Nippon Health Insurance (NHI) system, alleviating patients' payment for the drug themselves.