isozyme

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isoenzyme

 [i″so-en´zīm]
any of several forms of an enzyme that all catalyze the same reaction but may differ in reaction rate, inhibition by various substances, electrophoretic mobility, or immunologic properties. Several enzymes, particularly alkaline phosphatase, lactate dehydrogenase, and creatine kinase, have clinically important isoenzymes. Isoenzymes are separated by electrophoresis, and the pattern indicates which damaged organ has released the enzymes.

i·so·en·zyme

(ī'sō-en'zīm),
An enzyme (one of a group) that catalyze the same reaction but may be differentiated by variations in physical properties, such as isoelectric point, electrophoretic mobility, kinetic parameters, or modes of regulation, for example, lactate dehydrogenase, a tetramer composed of varying amounts of α and β subunits (that is, 4α, 3α + 1β, 2α + 2β, 1α + 3β, and 4β).
Synonym(s): isozyme

isozyme

/iso·zyme/ (i´so-zīm) one of the multiple forms in which an enzyme may exist in an organism or in different species, the various forms differing chemically, physically, or immunologically, but catalyzing the same reaction.

isozyme

(ī′sə-zīm′)
n.
An isoenzyme.

i′so·zy′mic adj.

isozyme

See isoenzyme.

i·so·en·zyme

(ī'sō-en'zīm)
One of a group of enzymes that catalyze the same reaction but may be differentiated by variations in physical properties, such as isoelectric point, electrophoretic mobility, kinetic parameters, or modes of regulation.

isozyme

see ISOENZYME.

isozyme

isoenzyme.
References in periodicals archive ?
Instead, one of the more thoroughly studied fluoroquinolones, ciprofloxacin, has been shown to have an inhibitory effect on the P-450 1A2 isozyme (26) involved in the metabolism of R-warfarin.
The [delta]-aminolevulinate dehydratase polymorphism: higher blood lead levels in lead workers and environmentally exposed children with the 1-2 and 2-2 isozymes.
Expression of a moderately anionic peroxidase is induced by aluminum treatment in tobacco cells: Possible involvement of peroxidase isozyme in aluminum ion stress.
Most recently, complexed structures of a naturally occurring variant of human pi-class glutathione S-transferase isozyme 1-1 with either S-hexylglutthione or (9R, 10R)-9-(S-glutathionyl)-10-hydroxy-9, l0-dihydrophenanthrene bound at the active site were determined at resolutions of 1.
caroliniana be regarded as a single species, on the basis of RFLPs, isozymes, phosphorus deficiency symptoms and breeding experiment analysis.
The inhibition potencies of the respective inhibitors against both PPA isozymes were almost the same and in the order of 5-CQA > CA [much greater than] QA.
There are two isozymes of 5[varies]-reductase (Type 1 and Type 2), that are encoded by separate genes and have different biochemical and pharmacological properties.
Other topics of the 23 articles include the role of CYP1B1 in glaucoma, biomarkers of acute kidney injury, PKC isozymes in chronic cardiac disease, and the metabolomics approach to drug response and disease.
Phylogenetic relationships and genetic divergence among endemic species of Berberis, Gunnera, Myrceugenia and Sophora of the Juan Fernandez Islands (Chile) and their continental progenitors based on isozymes and nrITS sequences.
3) The super family CYP450 is further divided into subfamilies depending on the degree of homology in amino acid sequences between the isozymes.