isoenzyme

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isoenzyme

 [i″so-en´zīm]
any of several forms of an enzyme that all catalyze the same reaction but may differ in reaction rate, inhibition by various substances, electrophoretic mobility, or immunologic properties. Several enzymes, particularly alkaline phosphatase, lactate dehydrogenase, and creatine kinase, have clinically important isoenzymes. Isoenzymes are separated by electrophoresis, and the pattern indicates which damaged organ has released the enzymes.

i·so·en·zyme

(ī'sō-en'zīm),
An enzyme (one of a group) that catalyze the same reaction but may be differentiated by variations in physical properties, such as isoelectric point, electrophoretic mobility, kinetic parameters, or modes of regulation, for example, lactate dehydrogenase, a tetramer composed of varying amounts of α and β subunits (that is, 4α, 3α + 1β, 2α + 2β, 1α + 3β, and 4β).
Synonym(s): isozyme

isoenzyme

/iso·en·zyme/ (-en´zīm) isozyme.

isoenzyme

(ī′sō-ĕn′zīm′)
n.
An isoform that is an enzyme.

i′so·en·zy′mic adj.

isoenzyme

[ī′sō·en′zīm]
Etymology: Gk, isos + en, in, syme, ferment
a chemically distinct form of an enzyme. The various forms are distinguishable in analysis of blood samples, which aids in the diagnosis of disease. Different enzymes that catalyze the same physiological reaction may also exist as isoenzymes in different animal species. Also called isozyme.

i·so·en·zyme

(ī'sō-en'zīm)
One of a group of enzymes that catalyze the same reaction but may be differentiated by variations in physical properties, such as isoelectric point, electrophoretic mobility, kinetic parameters, or modes of regulation.

isoenzyme (isozyme)

one of a number of ENZYMES that catalyse the same reaction, but are qualitatively different from each other, for example in PRIMARY STRUCTURE.

Isoenzyme

One of a group of enzymes that catalyze the same reaction but are differentiated by variations in physical properties.

isoenzyme

any of the several forms of an enzyme, all of which catalyze the same reaction, but which may differ in reaction rate, inhibition by various substances, electrophoretic mobility or immunological properties. Several enzymes, particularly alkaline phosphatase, lactate dehydrogenase and creatine kinase, have clinically important isoenzymes. Isoenzymes are separated by electrophoresis, and the pattern indicates which damaged organ has released the enzymes.
References in periodicals archive ?
Electrophoresis analysis of isoenzymes is known to provide a reliable assessment in testing genetic purity of hybrids and inbred lines of maize (Orman et al.
John's wort can significantly affect concomitantly administered drug levels by induction of the CYP isoenzyme 3A4 and more resources are listing this same possible induction for garlic.
Electrophoresis was conducted at the same voltage as esterase isoenzyme electrophoresis, and the gel was stained using the method described in the study by Li et al.
Serum b2m and LD2 isoenzyme levels were determined in the subjects and the values were compared with healthy age and sex matched controls.
22,23) A search of the literature yields many studies reporting autoimmunity to CA isoenzymes in various autoimmune diseases.
PB induced forms of isoenzymes were probably sensitive to mercuric chloride treatment as is evident from their impaired activities.
Adenosine deaminase (ADA) isoenzymes ADA1 and ADA2: diagnostic and biological role.
There are several analytical methods for the identification and quantification of CK isoenzymes.
Both isoenzyme couples possess phosphotyrosine protein phosphatase activity also.
Allium is an active compound in garlic and is directly implicated in the induction of CYP 3A4, CYP 2C9, and CYP 2C19 isoenzymes.
The first is attributed to the peripheral conversion of androstenedione to testosterone by other 17-[beta]-HSD isoenzymes particularly isoenzyme five in extragonadal tissues.
There are multiple laccase genes, which is esponsible for the biochemical diversity of laccase isoenzymes [14].