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isoenzyme

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
isoenzyme /iso·en·zyme/ (-en´zīm) isozyme.
i·so·en·zyme (s-nzm)
n.
See isozyme.

iso·en·zymic (-zmk, -zmk) adj.

Isoenzyme
One of a group of enzymes that catalyze the same reaction but are differentiated by variations in physical properties.

isoenzyme
[ī′sō·en′zīm]
Etymology: Gk, isos + en, in, syme, ferment
a chemically distinct form of an enzyme. The various forms are distinguishable in analysis of blood samples, which aids in the diagnosis of disease. Different enzymes that catalyze the same physiologic reaction may also exist as isoenzymes in different animal species. Also called isozyme.

isoenzyme
any of the several forms of an enzyme, all of which catalyze the same reaction, but which may differ in reaction rate, inhibition by various substances, electrophoretic mobility or immunological properties. Several enzymes, particularly alkaline phosphatase, lactate dehydrogenase and creatine kinase, have clinically important isoenzymes. Isoenzymes are separated by electrophoresis, and the pattern indicates which damaged organ has released the enzymes.


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Isoenzyme analysis of 35 Toxoplasma gondii isolates and the biological and epidemiological implications.
The author is also not familiar with the role of multiple isoenzymes involved in the developmental course of 5"-reductase-2 deficiency.
Elevated skeletal muscle creatine kinase MB isoenzyme levels in marathon runners.
 
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