results from cellular processes that occur over time and is influenced by genetics.
of the skin may predispose the patient to xerosis, but it is not a foregone conclusion that all older adults will develop this troublesome condition.
proceeds at a genetically determined pace, primarily caused by the buildup of damaging products of cellular metabolism as well as an increasing biological aging of the cells.
Ultimately, aging of the skin is an inseparable combination of intrinsic aging
and photoaging, although the latter can remarkably exacerbate the rate and severity at which we age.
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is influenced by the natural passage of time (chronological), skin phototype (genetics), and hormone production (endocrine).
You can think of intrinsic aging
as natural or 'genetic' aging," explains Dr.
The clinical manifestations of intrinsic aging
are fine wrinkles, thin and transparent skin, loss of underlying fat leading to hollowed cheeks and eye sockets, dry and itchy skin, inability to perspire sufficiently, hair graying, hair loss or hirsutism, and thinning of nail plates (7).
We definitely see changes in the environment long before we start to see" signs of intrinsic aging
, Jones says.
In the mid-1950s, Denham Harman, an inorganic chemist-turned-biologist at the University of California (Berkeley), was the first to posit that "free radical reactions are involved in the aging changes associated with the environment, disease, and intrinsic aging
The Body Confident line of products includes Ageless Body Formula[TM] for intrinsic aging
, Skin Cell Defense Formula[TM] for skin cell protection, Ageless Beauty Formula[TM] to reduce the appearance of fine lines and wrinkles and Skin Detoxifying Formula[TM] to support the body's natural detoxification system.
Since the effects of intrinsic aging
and photodamage on skin are multi-factorial, no single ingredient can address them all," said Dr.