intraepithelial neoplasia


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intraepithelial neoplasia

An in situ carcinoma confined to an epithelium that may superficially penetrate adnexal glands, measuring < either 3 mm or 5 mm depending on the criteria used; IN is adjectivally modified according to site of origin. See CIN.
Intraepithelial neoplasia  
AIN  Anal intraepithelial neoplasia
CIN  Cervical intraepithelial neoplasia, see there.
DIN  Ductal intraepithelial neoplasia, see there.
OIN  Oral intraepithelial neoplasia
PAIN  Perianal intraepithelial neoplasia
PIN  Prostatic (or rarely Penile) intraepithelial neoplasia
VAIN  Vaginal intraepithelial neoplasia
VIN  Vulvar intraepithelial neoplasia

intraepithelial neoplasia

Abnormal cell growth that is found within epithelial cells but has not yet spread to neighboring, underlying, or distant tissues. Intraepithelial neoplasia is thought to be an early marker of some cancers, e.g., cancers of the breast, prostate, or uterine cervix. See: cervical intraepithelial neoplasia
See also: neoplasia
References in periodicals archive ?
Although, pancreatic intraepithelial neoplasia is considered a precursor lesion for pancreatic ductal adenocarcinoma, it may appear in non-neoplastic diseases such as acute or chronic pancreatitis [20].
Reporting precursors to invasive pancreatic cancer: pancreatic intraepithelial neoplasia, intraductal neoplasms and mucinous cystic neoplasm.
3 Here we present a case report of secondary vaginal cancer after complete hysterectomy due to myoma which was complicated by low-grade cervical intraepithelial neoplasia (CIN I) and human papilloma virus (HPV) infection.
HRA sensitivity in detecting anal intraepithelial neoplasia among different high-risk populations has been demonstrated to be about 69 to 93%, with a specificity ranging from 32 to 64%.
Multifocal high grade prostatic intraepithelial neoplasia is a significant risk factor for prostatic adenocarcinoma.
Estimated at the means, the incremental cost-effectiveness ratios indicated that immediate treatment was dominated by the other two management methods, although it did offer the lowest cost per case of cervical intraepithelial neoplasia detected and treated.
In a study in the May I issue of Clinical Cancer Research, the scientists wrote that the more a protein known as PTOV1 presents in high-grade prostatic intraepithelial neoplasia (HG-PIN)--pre-malignant lesions found in most cancerous prostates--the more likely that prostate biopsies will detect cancer.
It aids in the in vivo detection of cervical intraepithelial neoplasia.
In the late-stage clinical trial of the vaccine, Gardasil, among the 8,641 women aged 15-26 who completed the three-injection course of treatment, there were no cases of precancerous abnormal cell growth (vaginal intraepithelial neoplasia or vulvar intraepithelial neoplasia) caused by HPV type 16 or type 18.
Studies have shown that HIV-positive women were more likely to develop genital warts and cervical intraepithelial neoplasia (4) and were at increased risk for viral infections (5).

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