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interleukin
(redirected from Interleukins)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.03 sec.
interleukin /in·ter·leu·kin/ (-loo´kin) a generic term for a group of multifunctional cytokines that are produced by a variety of lymphoid and nonlymphoid cells and whose effects occur at least partly within the lymphopoietic system.
interleukin-2  (IL-2) one produced by T cells in response to antigenic or mitogenic stimulation, acting to regulate the immune response. It stimulates the proliferation of T cells and the synthesis of other T cell–derived cytokines, stimulates the growth and cytolytic function of NK cells to produce lymphokine-activated killer cells, is a growth factor for and stimulates antibody synthesis in B cells, and may promote apoptosis in antigen-activated T cells; it is used pharmaceutically as an antineoplastic.

in·ter·leu·kin (ntr-lkn)
n.
Any of a class of lymphokines that act to stimulate, regulate, or modulate lymphocytes such as T cells.

interleukin
[-lo̅o̅′kin]
one of a large group of proteins produced mainly by T cells and in some cases by mononuclear phagocytes or other cells. Interleukins participate in communication among leukocytes and are important in the inflammatory response. Most interleukins direct other cells to divide and differentiate. Each acts on a particular group of cells that have receptors specific to that interleukin.

interleukin (in·tr·lōōˑ·kin),
n any of the family of proteins produced by lymphocytes and macrophages in the presence of antigens; responsible for T-cell proliferation.

interleukin
Immunology Any of a family of cytokines produced by lymphocytes, monocytes, and other cells, which induce growth and differentiation of lymphoid cells and primitive hematopoietic stem cells;. See Biological response modifier.


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TECKI CCL25), and interleukins such as IL-10 and IL-5, indicating a possible involvement of DU in cancer development, autoimmune diseases, and T helper 2 polarization ofT cells.
After T-cell receptor stimulation, most patients also experience a decrease in the production of interleukins, possibly because of a defect in the signal transduction system of CD4 T cells.
Cytokine: proteins (such as interleukins, tumor necrosis factor, and interferons) that are secreted by immune cells.
 
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