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interleukin-13

   Also found in: Encyclopedia, Wikipedia 0.03 sec.
interleukin-13 (IL-13),
a protein produced by activated T cells that inhibits inflammatory cytokine production by peripheral blood monocytes. It suppresses cell-mediated immune responses and promotes B cell differentiation.


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nbsp;produce significant increases in inflammation-related white blood cells in the lungs of the mice, and they elevate blood levels of key markers of allergic reactions, including IgE, interleukin-5, and interleukin-13.
Malignant glioma cells, as compared to normal brain cells, express interleukin-13 (IL13) receptors at a high density.
The Company's Interleukin-1 Trap is in a Phase II trial for rheumatoid arthritis, and a dual Trap that blocks both Interleukin-4 and Interleukin-13 is in a Phase I trial for asthma and allergy.
 
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