interleukin-1

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Related to Interleukin 1: Interleukin 2

in·ter·leu·kin-·1

(in'tĕr-lū'kin),
A cytokine, derived primarily from mononuclear phagocytes, that enhances the proliferation of T-helper cells and the growth and differentiation of B cells. Il-1 induces the release of Il-2. When secreted in larger quantities, IL-1 is a mediator of inflammation, entering the bloodstream and causing fever, inducing synthesis of acute phase proteins, and initiating metabolic wasting. There are two distinct forms of IL-1:, α and β, both of which perform the same functions but represent different proteins.

interleukin-1

(ĭn′tər-lo͞o′kĭn-wŭn′)
n.
Any of a family of cytokines that are released by macrophages and other cells and stimulate the inflammatory response.

interleukin-1 (IL-1)

a protein with numerous immune system functions, including activation of resting T cells, endothelial cells, and macrophages; mediation of inflammation; and stimulation of the synthesis of lymphokines, collagen, and collagenases. IL-1 can also induce fever, sleep, adrenocorticotropic hormone release, and nonspecific resistance to infection.

in·ter·leu·kin-1

(in'tĕr-lū'kin)
A cytokine, derived primarily from mononuclear phagocytes, which enhances the proliferation of T-helper cells and growth and differentiation of B cells.

interleukin-1

A powerful polypeptide hormone produced by MACROPHAGES and fibroblasts that acts on LYMPHOCYTES to increase their ability to respond to ANTIGENS. Interleukin-1 is also responsible for resetting the temperature regulating mechanism at a higher level and thus causing fever, for the induction of the release of ACUTE PHASE PROTEINS, and for promoting the absorption of bone by OSTEOCLASTS.

in·ter·leu·kin-1

(in'tĕr-lū'kin)
A cytokine, derived primarily from mononuclear phagocytes, which enhances the proliferation of T-helper cells and growth and differentiation of B cells.

interleukin-1 (IL-1) (in´tərloo´kin),

n a protein with numerous immune system functions, including activation of resting T cells, and endothelial and macrophage cells, mediation of inflammation, and stimulation of synthesis of lymphokines, collagen, and collagenases. It can also induce fever, sleep, and nonspecific resistance to infection. A number of interleukin proteins with varying immune-response properties exist. They are identified by numbers of 1 through 8.