intercalated disc


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in·ter·ca·la·ted disc

a specialized intercellular attachment of cardiac muscle cells comprising gap junctions, fascia adherens, and occasionally desmosomes.

in·ter·ca·la·ted disc

(in-tĕr'kă-lā-tĕd disk)
A histologic feature of cardiac muscle, occurring at the junction of two myocardial cells; site of intercellular passage of ions and electrical impulses.
References in periodicals archive ?
Targeted deletion of mXin[alpha] gene, encoding an intercalated disc protein, leads to cardiac hypertrophy (Abstract).
Ablation of mXin[alpha] gene, encoding an intercalated discs protein (1), results in cardiac hypertrophy and cardiomyopathy with a reduction in connexin 43 expression (2).
The intercalated discs and the lateral borders were visualised by antibodies against cadherin and type IV collagen (for details see Bruel et al.
2) are tightly packed with obliquely striated myofibers and contact each other by small desmosomes and intercalated discs (Fig.
1983), intercalated discs of cardiac muscle (Zernig and Wiche, 1985), and focal contacts (Seifert et al.