insulin analog

(redirected from Insulin analogues)

insulin analog

A synthetic insulin in which small changes in the amino acid structure of the polypeptide result in changes in the onset, peak effect, or duration of the molecule's physiological effects. Insulin aspart, glargine, and lispro are all insulin analogues.
See also: analogue
References in periodicals archive ?
has entered a worldwide collaboration with Sanofi to discover and develop novel, engineered insulin analogues.
Insulin analogues have been the subject of controversy relative to their therapeutic superiority and in relation to regular insulin and NPH.
Keywords: Diabetes, Hypoglycaemia, Insulin analogues, Levels of prevention, Modern glucose lowering drugs.
This is the firm's third filing for biosimilar monoclonal antibodies, insulin analogues and other recombinant proteins to be accepted by the European Medicines Agency in 2016.
Human insulin analogues are extremely expensive therefore should seldom be used.
The advantages of insulin analogues (lower risk of hypoglycemia) are well-documented (5).
We presented a rare case of localized lipoatrophy after repetitive injections of insulin analogues detemir and aspart in an obese adult female patient with type 2 diabetes mellitus.
This study has the strengths of its large size, the good data it had on tumor type and covariants, its attempt to model the impact of a cumulative glargine dosage, and its ability to place the impact of glargine within the context of other insulin analogues.
5 December 2011 - Danish pharma major Novo Nordisk A/S (CPH:NOVO B) announced today positive results with its insulin analogues NovoMix 30, Levemir and NovoRapid, including better glucose control and improved rates of hypoglycaemia in patients with type 2 diabetes.
Concern has been expressed, moreover, about IGF-I receptor affinity and increased mitogenic potency of some of the insulin analogues.
In this last issue of our Journal, you will find some interesting papers which are "Biphasic insulin analogues in type 2 diabetes, expert panel recommendations," "Oxidative stress markers in metabolic syndrome," "Association of Sp1 Colagen Type lg1 gene polymorphisim with the bone mineral density," ganglioneuroma" and "Diabetic ketoasidosis.
While still well short of this ideal, new therapeutic insulin analogues are substantially closer to physiological profiles than older types of insulin still widely used in hospitals (3,7).