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COX-2 inhibitor
(redirected from Inhibitors of COX-2)

    Also found in: Encyclopedia, Wikipedia 0.04 sec.
COX-2 inhibitor (kkst)
n.
Any of a class of nonsteroidal anti-inflammatory drugs that cause fewer gastrointestinal side effects by selective inhibition of prostaglandin formation.
COX-2 inhibitor
Cyclooxygenase-2 inhibitor Pain management A class of analgesics with fewer side effects than those of conventional NSAIDs–which inhibit both cyclooxygenases–COX-1 and COX-2; COX-1 protects the gastric mucosa, preventing ulcers, bleeding, and other digestive tract problems. See COX-2, Prostaglandin.


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Based on this, Vioxx and Bextra may be associated with a higher risk of a heart attack because they are more potent inhibitors of COX-2 enzymes than Celebrex.
COX-2 inhibitors: what you need to know by National Women's Health Report
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