inflammation (redirected from Inflammation mediators)

inflammation /in·flam·ma·tion/ (in″flah-ma´shun) a protective tissue response to injury or destruction of tissues, which serves to destroy, dilute, or wall off both the injurious agent and the injured tissues. The classical signs of acute inflammation are pain (dolor), heat (calor), redness (rubor), swelling (tumor), and loss of function (functio laesa).inflam´matory

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acute inflammation  inflammation, usually of sudden onset, marked by the classical signs (see inflammation ), in which vascular and exudative processes predominate.

catarrhal inflammation  a form affecting mainly a mucous surface, marked by a copious discharge of mucus and epithelial debris.

chronic inflammation  prolonged and persistent inflammation marked chiefly by new connective tissue formation; it may be a continuation of an acute form or a prolonged low-grade form.

exudative inflammation  one in which the prominent feature is an exudate.

fibrinous inflammation  one marked by an exudate of coagulated fibrin.

granulomatous inflammation  a form, usually chronic, marked by granuloma formation.

hyperplastic inflammation  one leading to the formation of new connective tissue fibers.

interstitial inflammation  one affecting chiefly the stroma of an organ.

parenchymatous inflammation  one affecting chiefly the essential tissue elements of an organ.

plastic inflammation , productive inflammation, proliferous inflammation hyperplastic i.

pseudomembranous inflammation  an acute inflammatory response to a powerful necrotizing toxin, e.g., diphtheria toxin, with formation, on a mucosal surface, of a false membrane composed of precipitated fibrin, necrotic epithelium, and inflammatory white cells.

purulent inflammation  suppurative i.

serous inflammation  one producing a serous exudate.

subacute inflammation  a condition intermediate between chronic and acute inflammation, exhibiting some of the characteristics of each.

suppurative inflammation  one marked by pus formation.

ulcerative inflammation  that in which necrosis on or near the surface leads to loss of tissue and creation of a local defect (ulcer).

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in·flam·ma·tion (nfl-mshn)

n.

A localized protective reaction of tissue to irritation, injury, or infection, characterized by pain, redness, swelling, and sometimes loss of function.

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in·flame v.

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Inflammation

The body's immune reaction to presumed foreign substances like germs. Inflammation is characterized by increased blood supply and activation of defense mechanisms. It produces redness, swelling, heat, and pain.

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inflammation

Etymology: L, inflammare, to set afire

the protective or destructive response of body tissues to irritation or injury. Inflammation may be acute or chronic. Its cardinal signs are redness (rubor), heat (calor), swelling (tumor), and pain (dolor), often accompanied by loss of function. The process begins with a transitory vasoconstriction, then is followed by a brief increase in vascular permeability. The second stage is prolonged and consists of sustained increase in vascular permeability, exudation of fluids from the vessels, clustering of leukocytes along the vessel walls, phagocytosis of microorganisms, deposition of fibrin in the vessel, disposal of the accumulated debris by macrophages, and finally migration of fibroblasts to the area and development of new, normal cells. The severity, timing, and local character of any particular inflammatory response depend on the cause, the area affected, and the condition of the host. Histamine, kinins, and various other substances mediate the inflammatory process. inflammatory, adj.

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inflammation (in·fl·māˑ·shn),

n response of bodily tissues to a chemical or physical injury indicated by heat, redness, swelling, and pain.

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inflammation (in´flmā´shn),

n the cellular and vascular response or reaction to injury. Inflammation is characterized by pain, redness, swelling, heat, and disturbance of function. It may be acute or chronic. The term is not synonymous with
infection, which implies an inflammatory reaction initiated by invasion of living organisms.

inflammation, gingival,

n See gingivitis.

inflammation, granulomatous,

n a chronic inflammation in which there is formation of granulation tissue.

inflammation, periodontal,

n See periodontitis and gingivitis.

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inflammation

a localized protective response elicited by injury or destruction of tissues, which serves to destroy, dilute, or wall off both the injurious agent and the injured tissue.

The inflammatory response can be provoked by physical, chemical and biological agents, including mechanical trauma, exposure to excessive amounts of sunlight, x-rays and radioactive materials, corrosive chemicals, extremes of heat and cold, and infectious agents such as bacteria, viruses and other pathogenic microorganisms. Although these infectious agents can produce inflammation, infection and inflammation are not synonymous.

The classic signs of inflammation are heat, redness, swelling, pain and loss of function. These are manifestations of the physiological changes that occur during the inflammatory process. The three major components of this process are: (1) changes in the caliber of blood vessels and the rate of blood flow through them (hemodynamic changes); (2) increased capillary permeability; and (3) leukocytic exudation.

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acute inflammation

inflammation, usually of sudden onset, marked by the classic signs of heat, redness, swelling, pain and loss of function, and in which vascular and exudative processes predominate.

adhesive inflammation

promotes adhesion of adjacent surfaces.

atrophic inflammation

one that causes atrophy and deformity.

catarrhal inflammation

a form affecting mainly a mucous surface, marked by a copious discharge of mucus and epithelial debris.

chronic inflammation

prolonged and persistent inflammation marked chiefly by new connective tissue formation; it may be a continuation of an acute form or a prolonged low-grade form.

chronic inflammation bowel disease of sheep

a syndrome of unknown etiology, manifest with wasting, ill thrift and mortality or culling for poor production. Reported in England and Canada, it affects both housed and pastured sheep, predominantly in their first year of life, but cases up to three years-of-age have been seen. Affected sheep are dull and anorectic with pale mucous membranes and have fecal staining of the perineum. The rumen fill is reduced and the feces are soft and malodorous. Blood examination shows hypoalbuminemia, an elevated blood urea nitrogen and leukocytosis with neutrophilia. On postmortem there is a lymphocytic enteritis with gross thickening of segments or the entire or distal part of the small intestine. There is no evidence for Johne's disease or parasitic gastroenteritis and the syndrome has similarities to the proliferative enteropathies of swine and horses.

croupous inflammation

a homogeneous layer of exudate lying close to but detached from the underlying inflamed tissue, which is comparatively unharmed; may form a fibrinous cast.

diphtheritic inflammation

manifested by the development of a fibrinous exudate which is firmly attached to the underlying tissue, such that it cannot be removed except by tearing off a superficial layer.

exudative inflammation

one in which the prominent feature is an exudate.

fibrinous inflammation

one marked by an exudate of coagulated fibrin.

fibrous inflammation

leads to the development of fibrous tissue.

granulomatous inflammation

a form, usually chronic, attended by formation of granulomas.

hyperplastic inflammation

leads to the development of new connective tissue.

hypertrophic inflammation

leading to the enlargement of the affected tissues.

interstitial inflammation

inflammation affecting chiefly the stroma of an organ.

obliterative inflammation

inflammation within a vessel or viscus leading to occlusion of the lumen.

parenchymatous inflammation

inflammation affecting chiefly the essential tissue elements of an organ.

productive inflammation, proliferative inflammation

one leading to the production of new connective tissue fibers.

pseudomembranous inflammation

an acute inflammatory response to a powerful necrotizing toxin, e.g. Fusobacterium necrophorum toxin, characterized by formation on a mucosal surface of a false membrane composed of precipitated fibrin, necrotic epithelium and inflammatory leukocytes. See also diphtheritic inflammation (above).

purulent inflammation

suppurative inflammation.

serous inflammation

one producing a serous exudate.

specific inflammation

one due to a particular microorganism.

systemic inflammation response syndrome (SIRS)

a generalized inflammatory response with vasodilation of capillaries and postcapillary venules, increased permeability of capillaries, and hypovolemia. Depressed cardiac function and decreased organ perfusion follow. The various initiating stimuli include sepsis and septic shock, hyperthermia, pancreatitis, trauma, snake bite and immune-mediated diseases.

toxic inflammation

one due to a poison, e.g. a bacterial product.

traumatic inflammation

one that follows a wound or injury.

ulcerative inflammation

that in which necrosis on or near the surface leads to loss of tissue and creation of a local defect or ulcer.

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inflammation

A complex reaction that occurs in response to injury, infection, irritation, toxicity or hypersensitivity. The reaction is characterized by redness, heat, pain and swelling to different degrees. Treatment depends on the cause. See antiinflammatory drug; infection.

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inflammation

A response to injury which is characterized by pain, swelling, heat, redness, and/or loss of function. See Round cellinflammation.

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Patient discussion about Inflammation mediators.

Q. Does anyone know how to relieve chronic back pain due to inflammation and arthritis? I have tried OTC arthritis pain meds they don't offer much relief for me. I have had surgery for herniated disc. My doctor says that there is a lot of inflammation and arthritis in my back. You can't get Vioxx anymore. Is there an alternative?

A. Ice works better than any anti inflammatory for inflammation. Apply ice for 10 min, then off for 10 min, back and forth. Exercise is the best treatment for arthritis, as pain gets worse if your muscles are stiff. I would recommend going for walks. Some pools have arthritis programs to do water aerobics that are special for arthritis. There are other meds you can take, such as Celebrex. Hope this helps, God Bless

Q. I heard that omega 3 is good for autoimmune diseases- is that true? I have Rheumatoid Arthritis, and I take all sort of anti inflammatory drugs. And I heard I can take omega 3 and I’ll be able to cut down the medication.

A. Well, I have the same thing and I take omega 3 and it certainly helpful. But this is only after i checked up with my Dr. he actually recommended. He explained that it changes the amount of inflammatory fatty acids in your body. That it’s supposed to be a part of your diet anyway but people eat less of it than they should, so it’s ok. But consult your physician about it- you can never know.

Q. what is fragments of endocervical glandular mucosa with inflammation and squamous metaplasia fragments of endocervical glandular mucosa

A. It means that part of the mucose on the cervix area has changes from a certain kind of mucose cells to another, and that there is a bit of an inflammation around it. This should be brought to the knowledge of a gynecologist and be monitored by him/her.