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immunotoxin
(redirected from Immunotoxins)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
immunotoxin /im·mu·no·tox·in/ (im´u-no-tok″sin) any antitoxin.
im·mu·no·tox·in (my-n-tksn, -my-)
n.
A hybrid molecule formed by binding a toxin to a monoclonal antibody, used to destroy tumor cells.

immunotoxin (IT)
[-tok′sin]
a toxin that is attached to a monoclonal antibody and used to destroy a specific type of target cell. An example is the plant toxin ricin, which inhibits protein synthesis in tumor cells that are recognized by the antibodies to which ricin is attached.

immunotoxin
an antitoxin.


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Immunotoxins made with the antibodies and antibody fragments of the invention have improved cytotoxicity to CD22-expressing cancer cells.
Immunotoxins are drugs created by linking an antibody to a portion of bacterial or plant toxin to destroy cells expressing the molecule to which the antibody binds.
Vitetta and her colleagues encountered vascular leak syndrome when they began testing immunotoxins in cancer patients.
 
 
 
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