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immunotoxin |
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immunotoxin /im·mu·no·tox·in/ (im´u-no-tok″sin) any antitoxin.
immunotoxin (IT) [-tok′sin] a toxin that is attached to a monoclonal antibody and used to destroy a specific type of target cell. An example is the plant toxin ricin, which inhibits protein synthesis in tumor cells that are recognized by the antibodies to which ricin is attached. immunotoxin an antitoxin. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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One possibility is that persistent organochlorine pollutants such as polychlorinated biphenyls (PCBs) elicit immunotoxic effects that influence the production of specific antibodies. In vitro and in vivo studies have demonstrated adverse effects-- including immunotoxic, neurologic, respiratory, and dermal responses--after exposure to specific toxins, bacteria, molds, or their products. Laboratory studies demonstrated that the pesticides malathion, resmethrin and methoprene are immunotoxic in lobsters, and that sublethal pesticide-related changes to the immune systems of lobsters can occur at certain exposure levels (De Guise et al. |
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