immunotoxin

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immunotoxin

/im·mu·no·tox·in/ (im´u-no-tok″sin) any antitoxin.

immunotoxin

(ĭm′yə-nō-tŏk′sĭn, ĭ-myo͞o′-)
n.
A hybrid molecule formed by binding a toxin to a monoclonal antibody, used to destroy tumor cells.

immunotoxin (IT)

[-tok′sin]
a toxin that is attached to a monoclonal antibody and used to destroy a specific type of target cell. An example is the plant toxin ricin, which inhibits protein synthesis in tumor cells that are recognized by the antibodies to which ricin is attached.

immunotoxin

an antibody attached to a specific toxic agent that is used to destroy specific cancer cells. Although experimental at present, these so-called ‘magic bullets’ hold out great hope as a new form of cancer CHEMOTHERAPY.

immunotoxin

an antitoxin.
References in periodicals archive ?
From the results of the above studies it can be extracted that As in one way or the other is immunotoxic and lowers the immunity in the affected individuals.
In rodents PFOA has been shown to be carcinogen[ic] and immunotoxic, but whether this can be translated into information about its effect on humans is not clear.
Substances with neurotoxic effects during growth, immunotoxic or which disturb the endocrine system will be banned if they are considered to pose a significant risk.
In this guidance, it does not require testing (Note: It has been and continues to be FDA's policy not to mandate testing), but suggests that certain immunotoxic risks be further evaluated.
Nickel is a known haematotoxic, immunotoxic, neurotoxic, genotoxic, reproductive toxic, pulmonary toxic, nephrotoxic, hepatotoxic and carcinogenic agent.
Collectively, these persistent bioaccumulative toxicants (PBTs) potentially found in children's bodies are known to be neurotoxic, immunotoxic, carcinogenic, teraterogenic, endocrine disruptors, and are associated with a range of other problems, including learning disabilities, behavioral problems, low birth weight, and asthma.
97) The Report suggested that, given the lack of basic data on "the effects of pesticide exposure on neurotoxic, immunotoxic, [and] endocrine responses in infants and children," (98) and that when toxicity testing in relation to children reveals certain fetal development effects or testing in relation to post-fetal development is "incomplete," an additional ten-fold reduction in pesticide tolerances should be used.
Propylene glycol is a common ingredient in fragrances and is considered an immunotoxic chemical.
The effects of these isoflavones have recently received a great deal of attention because of their possible beneficial and adverse effects due to potential estrogenic and immunotoxic activities (Barrett, 2002; Munro et al.
When released into the environment, perchlorate becomes an environmental pollutant posing immunotoxic conditions in animals and possibly in plants.
In addition, functional tests to determine body toxicant burden and immunotoxic reactivity are included because they improve diagnostic precision and clinical outcomes.