immunophenotyping


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immunophenotyping

(ĭm″ū-nō-fēn′ă-tīp″ĭng, ĭ-mū″)
Differentiation among subsets of lymphocytes, using antibodies that select for identifying molecules on their cell membranes.
References in periodicals archive ?
BioDuro said its customers can now access this platform to support a range of drug discovery oncology and immunooncology studies--from immunophenotyping screens to xenograft pharmacology studies.
Objective: To evaluate Immunophenotyping patterns in Mixed-Phenotype Acute Leukemias (MPAL).
Instead, the primary clinical tool for predicting the multilineage potential of leukemic blasts is characterization of protein expression by immunophenotyping.
Flow cytometric immunophenotyping was first developed by immunologists in the late 1960s and early 1970s as a research tool that enabled their study of the immune system.
Pinnacle examines nearly 600 RNA biomarkers known to be associated with response to targeted therapeutics, while Paragon is an RNA-based immunophenotyping assay with broad applications to the field of immuno-oncology and beyond.
The diagnosis and classification of acute leukaemia is based on a multidisciplinary approach which includes the morphology, cytochemistry, immunophenotyping, karyotyping and molecular genetic analysis.
Further bone marrow aspiration and biopsy studies with immunophenotyping suggested the final diagnosis of acute myeloid leukemia (AML), which is a rare cause of pancytopenia.
Flow cytometric immunophenotyping of peripheral blood samples showed positive CD3 and CD7 expression.
Immunophenotyping by flow cytometry revealed: CD79b (77.
The cited authors' further state that, despite differences in isolation and culture procedures, immunophenotyping is relatively consistent among laboratories.
As multicolor flow cytometry is becoming a reality, applications, like immunophenotyping, will benefit from the advanced properties of these products," said Frost & Sullivan analyst Divyaa Ravishankar.