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class switching
(redirected from Immunoglobulin class switching)

   Also found in: Wikipedia 0.02 sec.
class
1. a group of similar objects or values selected as a part of a classification.
2. a taxonomic category subordinate to a phylum and superior to an order.
3. a group of variables all of which show a value falling between certain limits.

class action
an exemplary court case fought on behalf of a number of litigants who can expect to be treated in the same way as the contesting litigant.
class limits
the highest and lowest values eligible to be included in a class when data are being classified or grouped.
class mark
the value selected to represent all of the values in a class. It may be the median or average value.
class midpoint
the average of the upper and lower limits of a class.
class switching
when a B lymphocyte changes over from producing one type of immunoglobulins to another.

class switching
Physiology A step in the normal maturation of Hb during fetal development that requires switching from embryonal zeta chain, which is structurally similar to the α chain, and occurs on chromosome 16 to mature α chain production; β chain production is a 2-stage maturation process with early loss of the ε chain and the presence during fetal and early post-natal life of a γ chain, which ↓ as β chain expression is ↑. Cf Introduction to this volume: note.


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10) The latter involves studies that evaluate in vitro immunoglobulin biosynthesis induced by specific stimuli that may include selected cytokines to induce immunoglobulin class switching.
CD40L binding to the CD40 receptor activates certain CD40-associated proteins which play an essential role in the induction of T-cell dependent antibody formation and immunoglobulin class switching.
 
 
 
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