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immunofixation

   Also found in: Wikipedia 0.01 sec.
immunofixation
[-fiksā′shən]
a process by which antigens in a protein mixture are separated on an electrophoretic gel and identified by the application of labeled antibodies.


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Urine electrophoresis and immunofixation were positive for IgG kappa light chains.
Serum electrophoresis and immunofixation showed an increased [gamma]-globulin fraction with oligoclonal immunoglobulin G (IgG)[lambda] and IgG[kappa] components.
A "complete response" required 100 percent disappearance of M-protein (a marker of tumor burden); negative immunofixation testing; no increase in size or number of lytic bone lesions; and disappearance of soft tissue tumors (plasmacytomas).
 
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