immune response

response /re·sponse/ (re-spons´) any action or change of condition evoked by a stimulus.respon´sive

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acute phase response  a group of physiological processes occurring soon after the onset of infection, trauma, inflammatory processes, and some malignant conditions; it includes increase in acute phase proteins in serum, fever, increased vascular permeability, and metabolic and pathologic changes.

anamnestic response  secondary immune r.

autoimmune response  the immune response against an autoantigen.

conditioned response  a response evoked by a conditioned stimulus; a response to a stimulus that was incapable of evoking it before conditioning.

galvanic skin response  the alteration in the electrical resistance of the skin associated with sympathetic nerve discharge.

immune response  any response of the immune system to an antigenic stimulus, including antibody production, cell-mediated immunity, and immunological tolerance.

primary immune response  the immune response occurring on the first exposure to an antigen, with specific antibodies appearing in the blood after a multiple day latent period.

relaxation response  a group of physiologic changes that cause decreased activity of the sympathetic nervous system and consequent relaxation after stimulation of certain regions of the hypothalamus. They may be self-induced through techniques such as meditation and biofeedback.

secondary immune response  the immune response occurring on second and subsequent exposures to an antigen, with a stronger response to a lesser amount of antigen, and a shorter lag time compared to the primary immune response.

triple response (of Lewis)  a triphasic skin reaction to being stroked with a blunt instrument: first a red line develops at the site due to histamine release, then a flare develops around the red line, and lastly a wheal is formed as a result of local edema.

unconditioned response  an unlearned response, i.e., one that occurs naturally to an unconditioned stimulus.

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immune response

n.

An integrated bodily response to an antigen, especially one mediated by lymphocytes and involving recognition of antigens by specific antibodies or previously sensitized lymphocytes.

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Immune response

A response from the body to an antigen that occurs when the antigen is identified as foreign and that induces the production of antibodies and lymphocytes capable of destroying the antigen or making it harmless.

Mentioned in: Antirheumatic Drugs, Ataxia-Telangiectasia, Blood Typing and Crossmatching, Contact Dermatitis, Immunologic Therapies, Immunosuppressant Drugs

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immune response,

a defense function of the body that protects the body against invading pathogens, foreign tissues, and malignancies. It consists of the humoral immune response and the cell-mediated immune response. In the humoral immune response, B lymphocytes produce antibodies that react with specific antigens. The antigen-antibody reactions activate the complement cascade, which causes the lysis of cells bearing those antigens. The humoral response may begin immediately on invasion by an antigen or up to 48 hours later. In the cell-mediated immune response, T lymphocytes mobilize tissue macrophages in the presence of foreign antigens. Also called immune reaction. See also humoral immunity, immune system.

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immune

1. being highly resistant to a disease because of the formation of humoral antibodies or the development of immunologically competent cells, or both, or as a result of some other mechanism, such as interferon activities in viral infections.

2. characterized by the development of antibodies or cellular immunity, or both, following exposure to antigen.

3. produced in response to antigen, such as immune serum globulin. The essential feature of antibody and cell-mediated immunity is that they are highly antigen specific.

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immune adherence

the binding of antibody-antigen-complement complexes to complement receptors found on red blood cells.

immune complex

see antibody-antigen complex.

immune complex disease

disease induced by the deposition of or association with antigen-antibody-complement complexes in the microvasculature of tissues. Fixation of complement component C3 by the complexes initiates inflammation. See also serum sickness, hypersensitivity.

immune complex reaction

type III hypersensitivity (1).

immune deficiency disease

one in which animals have inadequate immune responses and so are more susceptible to infectious disease. The defect may be primary (inherited), or secondary (acquired) which usually develops after birth because of toxins or infectious agents. See also combined immune deficiency syndrome, hypogammaglobulinemia, agammaglobulinemia, inherited parakeratosis, chediak-higashi syndrome and canine granulocytopathy syndrome.

immune hemolysis

see immune-mediated hemolytic anemia (below).

immune interferon

see interferon.

immune modulator

see immunomodulation.

immune reaction

immune response.

immune reaction fever

aseptic fever occurring in anaphylaxis, angioedema.

immune response

the specific response to substances interpreted by the body as not-self, the result being humoral and cellular immunity. The immune response depends on a functioning thymus and the conversion of stem cells to B and T lymphocytes. These B and T lymphocytes contribute to antibody production, cellular immunity and immunological memory. See also humoral immunity.

immune response (Ir) genes

see immune response genes.

immune surveillance

the detection by lymphocytes, especially T lymphocytes, of new antigens, particularly on tumor cells.

immune system

consists of the primary lymphoid organs (thymus and Bursa of Fabricius or its equivalent (bone marrow) in mammals) and secondary lymphoid organs (lymph nodes, spleen and other lymphoid tissue).

immune tolerance

see immunological tolerance.

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response

any action or change of condition evoked by a stimulus.

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autoimmune response

the immune response in which antibodies or immune lymphoid cells are produced against the body's own tissues.

conditioned response

see also conditioned response, conditioning.

dazzle response

shining a bright light in the eye causes a blink. Called also dazzle reflex.

galvanic skin response

the alteration in the electrical resistance of the skin associated with sympathetic nerve discharge.

immune response

specifically altered reactivity of the animal body after exposure to antigen, manifested as antibody-production, cell-mediated immunity, development of hypersensitivity, or as immunological tolerance. Called also immune reaction. See also immune response.

maze response

a test of vision for animals.

placing response

see placing reflex.

response rate

in surveys, the number of completed survey instruments (questionnaires, interview records) divided by the total number of persons approached.

response trial

a field trial conducted to test a hypothesis, often about the cause of a disease but can encompass therapeutics or control of a disease. The hypothesis is tested by observing the response to an alteration in the system, e.g. in feeding or in management.

triple response (of Lewis)

a physiological reaction of the skin to stroking with a blunt instrument: first a red line develops at the site of stroking, owing to the release of histamine or a histamine-like substance, then a flare develops around the red line, and lastly a wheal is formed as a result of local edema.

unconditioned response

an unlearned response, i.e. one that occurs naturally. See also conditioning.

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immune response

Immunology The constellation of responses of the immune system to foreign antigenic stimuli