![]() 1,017,763,175 visitors served. |
|
![]() Dictionary/ thesaurus | ![]() Medical dictionary | ![]() Legal dictionary | ![]() Financial dictionary | ![]() Acronyms | ![]() Idioms | ![]() Encyclopedia | ![]() Wikipedia encyclopedia | ? |
Imitrex |
Also found in: Dictionary/thesaurus, Wikipedia | 0.03 sec. |
sumatriptan succinate Imigran (UK), Imitrex Pharmacologic class: Selective 5-hydroxytryptamine1 (5-HT1) agonist Therapeutic class: Vascular headache suppressant Pregnancy risk category C ActionSelectively activates vascular 5-HT1 receptor sites, causing vasoconstriction in intracranial arteries AvailabilityInjection: 6 mg/0.5-ml prefilled syringes, 0.6 mg/0.5-ml vials, SELF dose injection kit (containing two prefilled syringes) Nasal spray: 5 mg in 100-mcl unit dose spray device (package of six), 20 mg in 100-mcl unit dose spray device (package of six) Tablets: 25 mg, 50 mg, 100 mg ⊘Indications and dosages ➣ Acute migraine Adults: Initially, 25 mg P.O.; if response inadequate after 2 hours, may give up to 100 mg P.O. If migraine recurs, repeat dose q 2 hours, not to exceed 200 mg/day. Or 6 mg subcutaneously, repeated as needed after 1 hour, not to exceed 12 mg in 24 hours. If P.O. therapy will follow subcutaneous injection, additional P.O. sumatriptan may be given q 2 hours, not to exceed 100 mg/day. Or a single dose of 5, 10, or 20 mg intranasally in one nostril, repeated p.r.n. in 2 hours, not to exceed 40 mg in 24 hours. Dosage adjustment• Hepatic impairment Contraindications• Hypersensitivity to drug PrecautionsUse cautiously in: Administration☞ If patient has risk factors for coronary artery disease, know that first dose should be given in medical setting with emergency equipment at hand.
Adverse reactionsCNS: headache, malaise, dizziness, drowsiness, fatigue, vertigo, anxiety, tight feeling in head, numbness CV: angina, chest pressure or tightness, transient hypertension, ECG changes, coronary vasospasm, myocardial infarction EENT: vision changes, nasal sinus discomfort, throat discomfort GI: abdominal discomfort, dysphagia Musculoskeletal: jaw discomfort, muscle cramps, myalgia, neck pain or stiffness Skin: flushing; tingling; warm, cool or, burning sensation Other: injection site reaction, feeling of heaviness or tightness InteractionsDrug-drug. Dihydroergotamine, ergotamine, methysergide: increased risk of vasospastic reaction Lithium, MAO inhibitors, selective serotonin reuptake inhibitors: weakness, hyperreflexia, incoordination Drug-herbs. Horehound: enhanced serotonergic effects Patient monitoring☞ Monitor cardiovascular status closely. Be aware that drug may cause serious and possibly fatal cardiac disorders. Patient teaching• Instruct patient to take as soon as possible after migraine onset. |
|
? Mentioned in | ? References in periodicals archive | |
|---|---|---|
The actress, who has had success with Imitrex (sumatriptan), is expecting twins with her husband, Tom Mahoney, and says she won't be taking any medication for the foreseeable future. In September, GlaxoSmithKline, maker of such commonly used medications as the migraine medicine Imitrex and antidepressant Paxil, launched several newspaper advertisements that question the safety and quality of medications ordered through Canadian Web sites as part of its campaign against importation of prescription drugs. For example, folks who get migraines often use a prescription medication called Imitrex. |
| Free Tools: |
For surfers:
Browser extension |
Word of the Day |
Help
For webmasters: Free content | Linking | Lookup box | Double-click lookup | Partner with us |
|
|---|