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imiglucerase

   Also found in: Wikipedia 0.01 sec.
imiglucerase /im·i·glu·cer·ase/ (im″ĭgloo´ser-ās) an analogue of glucosylceramidase, for which it is used as an enzyme replenisher in type 1 Gaucher's disease.
imiglucerase,
an analog of a human enzyme produced by recombinant deoxyribonucleic acid technology.
indications It is prescribed as enzyme replacement therapy for patients with type I Gaucher disease.
contraindications There are no known contraindications to the use of imiglucerase by injection.
adverse effects The side effects most often reported include headache, nausea, abdominal discomfort, dizziness, and rash.

imiglucerase [im″ĭ-gloo´ser-ās]
an analogue of the enzyme lacking in Gaucher's disease, used for treating the adult form of the disease; administered by intravenous infusion.


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Since then, the Therapeutic Goods Administration has designated two biological drugs as orphans--rabies immunoglobulin and recombinant enzyme imiglucerase for replacement therapy in patients with Gaucher disease.
Saturating patient bases for human growth hormones and recombinant imiglucerase will preclude faster growth.
This therapy uses either imiglucerase or alglucerase, both of which are forms of the enzyme glucocerebrosidase.
 
 
 
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