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idarubicin/ida·ru·bi·cin/ (i″dah-roo´bĭ-sin) an anthracycline antineoplastic used as the hydrochloride salt in the treatment of acute myelogenous leukemia.
an antibiotic and antineoplastic.
indications This drug is used in combination with other antineoplastics for acute myelocytic leukemia in adults.
contraindications Pregnancy, hypersensitivity, lactation, and myelosuppression prohibit the use of this drug.
adverse effects Adverse effects of this drug include hypertension, extrasystoles, ventricular tachycardia, bundle branch block, atrioventricular block, palpitations, supraventricular extrasystoles, syncope, and nausea. Common side effects include headache, hypotension, and bradycardia. Life-threatening side effects include sinus arrest, congestive heart failure, and arrhythmias.
idarubicin4-demethoxydaunorubicin Oncology An antitumor antibiotic
idarubicinA CYTOTOXIC anti-cancer drug. A brand name is Zavedos.
an anthracycline antibiotic used as an antineoplastic agent; similar to doxorubicin.