IMP dehydrogenase


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IMP de·hy·dro·gen·ase

an enzyme that catalyzes the reaction of IMP, water, and NAD+ to form NADH and xanthosine 5'-monophosphate (XMP), the immediate precursor of GMP.
References in periodicals archive ?
Assignment of the human type I IMP dehydrogenase gene (IMPDH1) to chromosome 7831.
Chromosomal localization and structure of the human type II IMP dehydrogenase gene (IMPDH2).
Regulation of IMP dehydrogenase gene expression by its end products, guanine nucleotides.
Modulation of IMP dehydrogenase activity and guanylate metabolism by tiazofurin (2[beta]-D-ribofuranosylthiazole-4-carboxamide).
Growth inhibition and induction of phenotypic alterations in MCF-7 breast cancer cells by an IMP dehydrogenase inhibitor.
IMP dehydrogenase, an enzyme linked with proliferation and malignancy.
Proliferation-linked regulation of type II IMP dehydrogenase gene in human normal lymphocytes and HL-60 leukemic cells.
Expression of human IMP dehydrogenase types I and II in Escherichia coli and distribution in human normal lymphocytes and leukemic cell lines.