IL9


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IL9

A gene on chromosome 5q31.1 that encodes interleukin-9, a cytokine which regulates various haematopoietic cells, stimulating cell proliferation and preventing apoptosis. IL9 acts via interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins, linking it to various biological processes.
 
Molecular pathology
IL9 is a candidate gene for asthma.
References in periodicals archive ?
Ademas se activan los macrofagos, los cuales incrementan la produccion de citocinas, que intervienen en la informacion intercelular, las cuales se unen a receptores especificos de las celulas blanco, desencadenando la sintesis y liberacion de mediadores secundarios como factor activador de plaquetas, IFN, IL8, IL9, IL10 e IL13 que inducen la produccion de oxido nitrico, el cual produce vasodilatacion, produccion de prostaglandinas y leucotrienos, bradiquinina e histamina que a su vez activan macrofagos, polimorfonucleares e inicia un circulo inflamatorio.
IL9 leads to airway inflammation by inducing IL13 expression in airway epithelial cells.
1) Meteorological Service of Canada, Environment Canada, Place Bonaventure, 800 rue de la Gauchetiere Ouest, suite 7810, Montreal, Quebec H5A IL9, Canada; syIvain.
JAK-3 is a cytoplasmic protein tyrosine kinase (involved in signaling through the common gamma chain of several cytokine receptors: IL2, IL4, IL7, IL9, IL15, and IL21) in many hematopoietic cells, including B cells, T cells, and NK cells.