IL29

IL29

A gene on chromosome 19q13.13 that encodes interleukin-29, an immunomodulatory cytokine which upregulates MHC class-I antigen expression. It has potent antiviral activity and has antitumour activity. IL29 is a ligand for the heterodimeric class-II cytokine receptor composed of IL10RB and IL28RA, which is thought to act via the JAK-STAT pathway.
References in periodicals archive ?
LQ11/pLAU53, LQ12/pLAU53, LQ13/pLAU53, LQ14/pLAU53, and LQ15/pLAU53 strains were generated by P1transduction of (tetO) [sub]240 -Gm and (lacO) [sub]240 -Km cassettes from strains IL2 and IL29.
The strain IL29 has the kanamycin resistant lacO repeat cassette localized near the dif site (1803 kb position).