IL25

IL25

A gene on chromosome 14q11.2 that encodes interluekin-25, a proinflammatory cytokine that induces activation of NF-kappa-B and stimulates proinflammatory IL-8 production. IL25 favours Th2-type immune responses.
References in periodicals archive ?
This suggests that IL25 receptor signalling may provide a new therapeutic target for the treatment of breast cancer, she said.
The research team demonstrated that a molecule called IL25, a member of the IL17 cytokine family, promotes the accumulation of a lineage-negative multipotent progenitor cell population in the intestine that promotes T cell responses associated with asthma and helminth infection.
The ability of IL25 to induce the emergence of an MPP cell population identifies a link between the IL17 cytokine family and extramedullary haematopoiesis and suggests a previously unrecognized innate immune pathway that promotes TH2 cytokine responses at mucosal sites.