IL11


Also found in: Encyclopedia.

IL11

A gene on chromosome 19q13.3-q13.4 that encodes interleukin-11, a member of the gp130 family of cytokines, which drive the assembly of multi-subunit receptor complexes, all of which contain at least one molecule of the transmembrane signalling receptor IL6ST. IL11 directly stimulates the proliferation of haematopoietic stem cells and megakaryocyte progenitor cells, and it induces megakaryocyte maturation resulting in increased platelet production.
References in periodicals archive ?
Most efficient bacterial isolate IL11 was identified by 16S rRNA gene analysis.
Linkage and association of the CA repeat polymorphism of the IL11 gene, obesity-related phenotypes, and bone mineral density (BMD) in two independent Caucasian populations.
In [God] it is shown that an almost base point free divisor is nef, see also [Laz, IL11.
One conjectures that for arbitrary big line bundles the asymptotic algebraic multiplier of its multiples and its analytic multiplier ideal coincide, see [DEL] and also [Laz, IL11.
En el caso especifico de la diferenciacion de las celulas madre hematopoyeticas, el microambiente medular y las vias de senalizacion celular juegan un papel relevante; se han hecho numerosos ensayos in vitro para estudiar el papel de las interleuquinas (IL) en este proceso, en particular la IL-3, la IL-6 y la IL11.
Esta citoquina junto con la IL6 (Interleukina-6), vIL6 (Interleukina-6 viral a partir del virus herpes tipo 8) o tambien denominado virus del sarcoma de Kaposi, IL11 (Interleukina-1), OSM (Oncostatina M), CT1 (Cardiotrofina-1), CLC/BSF3 (Citoquina similar a la Cardiotrofina-1/Factor estimulante de la Linfopoyesis B tipo 3), NP (Neuropoyetina), IL27 (Interleukina-27), pertenecen a la familia de la IL6.